Schneier loves this idea
from MS, I don't see what the big deal is. Sounds like a modified version of an integrity checker to me.
Here's how it works: The user has the GhostBuster program on a CD. He sticks the CD in the drive, and from within the (possibly corrupted) OS, the checker program runs: stopping all other user programs, flushing the caches, and then doing a complete checksum of all files on the disk and a scan of any registry keys that could autostart the system, writing out the results to a file on the hard drive.
Then the user is instructed to press the reset button, the CD boots its own OS, and the scan is repeated. Any differences indicate a rootkit or other stealth software, without the need for knowing what particular rootkits are or the proper checksums for the programs installed on disk.